Creating Serial profile.
Go to Big6–>Profiles Configuration and select “Serial” from the top bar and press “+” buton to create new or edit to edit existing. This will pop-up
Select existing serial port from your computer. The serial port MUST be existing in your HS4 computer. Also it is your HS4 computer where you adjust the properties of the serial port to match those of your serial device. Such properties include speed, parity, number of stop bits, handshaking (such as RTS/CTS) etc. Do not expect to setup those in Big6. Choose connection speed (in the example 9600 bits per seconds a.k.a. Baud rate).
See “Create a profile” page for setting up the the rest of the profile. Everything below the middle horizontal line is same for all profiles and covered very well in “Create a profile” section.